There is usually something that triggers the condition, like an infection. However, people with these genes do not automatically develop RA. Researchers believe that some people have genes that can make them more likely to have RA. This leads to increased pain and inflammation, as well as deformities. As the condition gets worse, ligaments, joints, and cartilage become more damaged. In some cases, RA is symmetrical, which means it affects the same joints on both sides of the body. The extra synovial fluid also stretches out the synovium, which makes your joints far less stable. This causes pain and stiffness in the ankle joints. This leads to extra synovial fluid, which in turn creates more swelling and inflammation. RA specifically affects the synovial joints by causing them to swell and thicken. This means that the body’s immune system attacks its own healthy tissues. Rheumatoid arthritis is an autoimmune condition.
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